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Se vio que mientras GLP-1 tiene efectos glucagonostticos y lipolticos indirectos, el GIP favorece la lipognesis y tiene un rol glucagonotrpico durante la hipoglucemia

We also provide an assessment of body weight loss and nausea induced by semaglutide and tirzeapatide across patients with obesity and T2D in the STEP 2 and SURPASS 2 trials compared to those with obesity but not T2D in the STEP 1 and SURMOUNT 1 trials ( Figure 2 )